Forums Health Best probiotics to buy? Reply To: Best probiotics to buy? May 9, 2018 at 9:50 am #186 FUZZY 15 Posts Whether they’re tasty – they probably won’t have any other benefits. There are large scale prospective studies showing reduction in the clinical signs of allergic disease in children when used in pregnancy and the first three months of nursing (in allergic mothers), with some experimental data of increased tolerance to allergens in the bowel due to IL-10 induction. These products do have some beneficial effects, but when they should be used is not completely clear. Even a short course of antibiotics devastates the diversity of bacteria in the bowel and on the skin. A high fibre diet may also have considerable beneficial results. This is all quite early science, but manipulating the microbiome has considerable potential.